Teflex belongs to a class IV (not dangerous) of low toxic substances by way of intragastric and cutaneous administration.
Teflex does not exhibit any local irritating effect on the skin of experimental animals.
Teflex renders a weak irritating effect on the eye mucous membrane of tested animals.
Teflex does not possess any skin absorption activity.
Teflex belongs to the III ( the lowest) class of allergenic activity meaning,
Teflex is not demonstrating any allergic reaction what-so-ever.
For more detailed information on safety and toxicity, please refer to the "EVALUATION OF TOXICITY AND SAFETY OF APPLICATION OF DISINFECTING FORMULATION TEFLEX" made available in the Press Centre section on our website.
"Sub Acute Toxicity"
The active ingredient in Teflex (guanidine modified copolymer) has no mutagenic effect. All chronic exposure experiments of Teflex showed that doses of less 50 mg/kg are harmless to microorganisms. At this dosage, Teflex does not affect the development and function of the ova or sperm cells, testes or ovaries. Furthermore, it has no effects on the menstrual cycle. Teflex has no embryo toxic effect, it does not cause mutations in somatic as well as sexual cells and it does not induce tumor formation. In some situations where Teflex was administered per dose (taken orally, this is not recommended of course), it resulted in anemia because of its membranotoxic effect on the cellular membrane. However, it is important to note that this effect occurred on experimental animals at intrastomach administrations during chronic exposure and using a very high dose of the Teflex concentrate. The safe limit value for Teflex (CSF = LD50 / ED 100) is calculated on average as 3667. On multiple occasions, it was demonstrated that Teflex was more toxic for microorganisms than it was for humans, plants and animals.
For more detailed information on this subject, please refer to the "EVALUATION OF TOXICITY AND SAFETY OF APPLICATION OF DISINFECTING FORMULATION TEFLEX made available in the Press Centre section on our website.